Distinct but concerted roles of ATR, DNA-PK, and Chk1 in countering replication stress during S phase. damage and promotes apoptosis in CPT-treated cells. Taken together our results suggest that Stau2 is an anti-apoptotic protein that could be involved in DNA replication and/or maintenance of genome integrity and that its expression is regulated by E2F1 via … Read more
Whiskers were drawn between the highest and lowest data points within 1.5 interquartile range (IQR) from the upper or lower quartile. as well as reduced histone H3K27 acetylation in several key glycolysis Kdr genes. Furthermore, deficiency sensitizes MEFs to 2-deoxy-D-glucose, a competitive inhibitor of glycolysis, to induce cell blebbing. Activated Rapgef1, a Crk/Crkl-downstream effector, rescues … Read more
Using its short lifespan and high embryo accessibility and number, the turquoise killifish is uniquely well-suited to review the partnership between diapause and aging also to understand how top features of suspended animation could possibly be harnessed. Acknowledgements J.J.R. between your select few model microorganisms and the rest resulted in a steady linguistic change in … Read more
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