9a, d, e), thus confirming the importance and generalization of PGE2/COX2 signalling during development of chemoresistance, while other metabolites of the arachidonic acid pathway may also be involved
9a, d, e), thus confirming the importance and generalization of PGE2/COX2 signalling during development of chemoresistance, while other metabolites of the arachidonic acid pathway may also be involved. repopulation can be abrogated by a PGE2-neutralizing antibody and celecoxib drug-mediated blockade of PGE2 signalling. administration of the cyclooxygenase-2 (COX2) inhibitor celecoxib effectively abolishes a PGE2- and … Read more